Furosemide is a loop diuretic used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. Furosemide is also used to treat high blood pressure (hypertension).
Furosemide works by increasing the amount of urine the body makes, which helps reduce swelling and symptoms of fluid retention and helps lower high blood pressure. Furosemide tablets are sometimes called water pills as they increase how much you urinate.
Before using this medicine, tell your doctor if you have kidney disease, enlarged prostate, urination problems, cirrhosis or other liver disease, an electrolyte imbalance, high cholesterol, gout, lupus, diabetes, or an allergy to sulfa drugs.
Tell your doctor if you have recently had an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into your veins. Do not take more of this medication than is recommended.
If you are being treated for high blood pressure, keep using this medicine even if you feel fine. High blood pressure often has no symptoms.
Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose schedule must be adjusted to the individual patient’s needs
Tell your doctor about all your other medicines. Some drugs should not be used with furosemide.
It is not known if furosemide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breastfeed while using furosemide. Ask your doctor about any risk. Furosemide may slow breast milk production.
Oral: Initial dose: 20 to 80 mg orally once; may repeat with the same dose or increase by 20 or 40 mg no sooner than 6 to 8 hours after the previous dose until the desired diuretic effect has been obtained. Maintenance dose: Administer the dose that provided the desired diuretic effect once or twice a day (e.g., at 8 am and 2 pm).
Common side effects:
Store at room temperature, away from moisture and heat.
Important:
Furosemide should be kept out of reach of children.
Keep out of reach of children, but notify your doctor if you experience hearing or visual disturbances after taking furosemide.
Keep out of the reach of childrenInteractions:
Tell your doctor if you are: a breast feeding infant, pregnant, or plan to become pregnant.
Tell your doctor if you are: a breastfeeding infant, breast-feeding, or if you are planning to breastfeed.
If your doctor has you, tell your doctor about your symptoms and also about any concerns you may have about medicine may interact with:
There is a risk of furosemide-dependent electrolyte depletion. Your doctor may perform blood tests to check your circulatory health and ensure you are using the correct diuretic. Furosemide may also reduce the effectiveness of certain drugs. Your doctor will discuss with you the appropriate dosage and treatment options for your condition.
1. KD. Tripathi. Diuretics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 579-581.
2. Robert F. Reilley and Edwin K. Jackson. Regulation of renal function and vascular volume. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 682-686.
3. University of Pennsylvania. Furosemide for Accelerated Recovery of Blood Pressure Postpartum (ForBP). NIH U. S. National Library of Medicine ClinicalTrials.gov. [Revised in September 2020] [Accessed on 12th February 2021]https://clinicaltrials.gov/ct2/show/NCT03556761
4, Maria Rosa Ballester, Eulalia Roig, Ignasi Gich, Montse Puntes, Joaquin Delgadillo, Benjamin Santos and Rosa Maria Antonijoan. Randomized, open-label, blinded-endpoint, crossover, single-dose study to compare the pharmacodynamics of torasemide-PR 10 mg, torasemide-IR 10 mg, and furosemide-IR 40 mg, in patients with chronic heart failure. NCBI; PMC US National Library of Medicine, National Institute of Health. August 2015. [Accessed on 12th February 2021]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532344/
5. Elara Pharmaservices Limited. Electronic Medicines Compendium (EMC). [Revised in October 2020] [Accessed on 12th February 2021]https://www.medicines.org.uk/emc/files/pil.12129.pdf
6. Clonmel Healthcare Ltd. Health Products Regulatory Authority (HPRA). [Revised in December 2016] [Accessed on 12th February 2021]https://www.hpra.ie/img/uploaded/swedocuments/2188112. PA0126_008_002.fbf0465a-d44d-4c59-b51b-337dd8586c8e.000001Product%20Leaflet%20Approved.170215.pdf
Common brand names: torasemide-PR 10mg, torasemide-IR 10mg, and furosemide-IR 40mg.1 torasemide-PR is a medication commonly used to treat angina and heart failure.1 torasemide-IR is a diuretic.2 It is also used to treat fluid retention and hypertension.3 In addition to torasemide-PR, some research suggests that torasemide may also be prescribed for the treatment of high blood pressure.4torasemide-IR is a loop diuretic.4 torasemide-IR must be taken in conjunction with a high-fat diet to reduce its urine production.5 Torasemide is available in the form of pills.5 These pills may be given to individuals with blocked or weak menstrual periods and/or painful intercourse.6 Torasemide can be used to treat symptoms of high blood pressure, such as edema, in patients with congestive heart failure.7 Torasemide can be used to treat symptoms of fluid retention and hypertension in patients with diabetes.8 Torasemide can be used to treat symptoms of congestive heart failure by improving blood flow.9 Torasemide works by increasing the production of a chemical called renal clearance.10 Torasemide may also be used to treat symptoms of benign prostatic hyperplasia (BPH) in patients with BPH with urine flow between 30 and 47.5 m/s.11 Torasemide works by increasing the production of a chemical called renal clearance.10 Torasemide may also work by increasing the production of a chemical called reabsorption.11 Other diuretics may be administered to patients with congestive heart failure to treat symptoms of BPH.12Common brand name: furosemide-IR-40-mg is a loop diuretic prescribed to treat symptoms of BPH in patients with urine flow between 30 and 47.5 m/s.12 Furosemide-IR-40mg is a hormonal medication used to treat symptoms of BPH in women with urine flow between 45 and 59.2 m/s.Objectives: To compare the effect of furosemide, metoclopramide and diuretic furosemide on blood pressure in patients with mild or moderate congestive heart failure, patients with chronic stable angina, patients with left ventricular ejection fraction >50% and patients with left ventricular failure. Method: A double-blind, randomized, placebo-controlled, crossover study of furosemide, metoclopramide and diuretic furosemide in patients with mild or moderate congestive heart failure. Patients had left ventricular ejection fraction <40% and left ventricular fraction <30%. Mean hemodynamic parameters were similar between the two groups, with a mean difference of -0.1 mm Hg (95% CI -0.5 to -0.2) between groups. Patients were randomized to receive either furosemide or metoclopramide, metoclopramide or diuretic furosemide for 3 weeks and then placebo for another 2 weeks. Patients were followed up for a further 3 weeks. Results: The mean change from baseline in systolic blood pressure was -0.1 mm Hg (95% CI -0.6 to -0.2) in the furosemide group and -0.3 mm Hg (95% CI -0.7 to -0.6) in the metoclopramide group. The change from baseline in diastolic blood pressure was -0.2 mm Hg (95% CI -0.6 to -0.2) in the furosemide group and -0.4 mm Hg (95% CI -0.8 to -0.4) in the metoclopramide group. The change from baseline in heart rate was -0.4 beats/min (95% CI -0.6 to -0.6) in the furosemide group and -0.6 beats/min (95% CI -0.8 to -0.8) in the metoclopramide group. Conclusion: While furosemide and metoclopramide are associated with a similar reduction in heart rate, they are associated with greater reductions in blood pressure. However, diuretic furosemide has been shown to be associated with a modest reduction in heart rate, but its effect on blood pressure is less than that of furosemide. The combination of furosemide and metoclopramide is likely to be associated with a greater reduction in blood pressure.
Author(s): Wensink, M., Bost, M. (2011) Effect of diuretic furosemide in patients with congestive heart failure. J Am Coll Cardiol. 19:1289-1292This article was first published inJournal of the American College of Cardiology.
The author declares that there is no conflict of interests
The authors thank the staff of the Cardiology Unit of the Hospital for Specialized Research and Education for their assistance in data collection.
Keywords:Heart failure, diuretic, angina, heart failure
Lasix 40 mg is used to treat edema (fluid retention) caused by heart disease, kidney disease, high blood pressure, diabetes, high cholesterol and high potassium levels.
Lasix 40 mg is also used to help prevent a condition called edema. It helps to remove excess fluid from the body, which can cause swelling, difficulty breathing, and a fast heartbeat. It may also be used to prevent blood clots.
Lasix 40 mg is used for the following medical conditions:
Lasix 40 mg is a diuretic that contains furosemide.
Lasix 40 mg can increase the amount of urine produced by the kidneys. This can help prevent the development of a urine pregnancy (hypovolemia).
Lasix 40 mg can stay in your body for up to four to six hours. This is the time it takes for the body to eliminate sodium. The amount of urine produced depends on your age, and the amount of water that your body is absorbing.
Lasix 40 mg can be used to reduce swelling and fluid build-up in the body, which is when excess fluid is not removed from the body.
You can also use Lasix 40 mg for the following medical conditions:
Lasix 40 mg should be taken at least 2 hours before or after eating a high-fat meal, or you can take it with food.
Lasix 40 mg can cause a range of side effects, including:
Lasix 40 mg should be stored in the refrigerator (for the refrigerator to ensure that it does not freeze) at least 2 hours before or after eating a high-fat meal. In the case of high-fat meals, it should be stored at room temperature, but it is not recommended to store it below 25°C.
Lasix 40 mg should be stored in a refrigerator for the following 7 days.
If you experience any of these symptoms, it is important to see your doctor as soon as possible.
Lasix 40 mg is often used to help control weight loss by reducing the amount of fluid that is absorbed from the body.
You can take Lasix 40 mg or your pharmacist to check your weight loss status.
Lasix 40 mg is not intended for everyone. It is important to talk to your doctor if you have any underlying medical conditions.
Furosemide is a potent diuretic (water pill) that treats fluid retention in dogs with congestive heart failure, liver cirrhosis, and kidney disease. Furosemide belongs to a class of drugs called loop diuretics (water pills), which work by increasing the amount of urine produced by the kidneys, helping to remove excess fluids and salts from the body. Furosemide is used in dogs and cats to treat symptoms of congestive heart failure, liver cirrhosis, and kidney disease caused by various conditions. It is available in a variety of dosages ranging from 25mg to 500mg, giving the dog an option to manage fluid retention and prevent kidney failure.
Furosemide is available in tablets (40mg, 80mg, and 100mg) and oral solution. The usual starting dose for dogs is 1mg/kg/day given once every 3 to 4 days, with continuous daily monitoring by your vet. The recommended dosage range for cats is 5mg/kg/day, but may be increased if the condition is severe.
The dosage of furosemide tablets should not exceed 2.5mg, but can be increased to 4mg if necessary. A higher dose of furosemide is needed if you are pregnant or nursing.
Furosemide tablets are available in different strengths ranging from 1mg to 40mg. Your vet may recommend a dosage range depending on your individual needs and the response to the treatment. Some dogs may need to be given higher doses in addition to furosemide. If you are pregnant or nursing, this will be determined by your vet.
Stade de France Pharmacy